YPL+ Database       Yeast Protein Localization Plus Database
Yeast Genetics and Molecular Biology Group (YGMBG) University Graz




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Welcome to the Yeast Protein LocalizationPlus Database, YPL+.db

This image database provides information about the subcellular localization of proteins in live yeast (Saccharomyces cerevisiae) cells, obtained by high-resolution confocal imaging. The imaged cells are derived from the collection of GFP fusion constructs that were generated by C-terminal chromosomal tagging (Huh et al., 2003, Nature 425, 686-691) and the collection of proteins involved in lipid-metabolism, constructed by in vivo recombination (Natter et al., 2005, Mol. Cell. Proteomics 4(5), 662-672).

Use of information provided by YPL+.db in publications should be referenced as ‘Oskolkova, Leitner and Kohlwein, personal communication’.

Please note: as with all tagging techniques, GFP tagging may alter the function and localization of the protein under study. Although we noted that most of the localization patterns appear to be consistent with other available data, we provide this information ‘as is’, without any warranty for its correctness. See also Wolinski et al., 2009, Methods in Molecular Biology, Vol 548, pp75-99, for potential pitfalls and limitations of yeast live cell imaging.

This project is supported by: